ONCOBIOLOGY : index

ONCOBIOLOGY : EXPERIMENTAL SCHEMES

ONCOBIOLOGY : OSTEOPOROSIS


EXPERIMENTAL PROTOCOL OF A PHYTOTHERAPEUTIC TREATMENT FOR THE STOMATOLOGICAL COMPLICATIONS IN AIDS AND TERMINAL CANCER PATIENTS

by C. DURAFFOURD (M.D.) & J.C. LAPRAZ (M.D.)

OBJECTIVES

To demonstrate the anti-infectious, analgesic and cicatrizing properties of a stomatological phytotherapeutic treatment.

MEANS

Applying a phytotherapeutic to AIDS and terminal cancers patients, in order to sterilize their often infected mouth, reduce their local pain and facilitate the cicatrization of all types of sores, which are consequences of both their illness and the treatments, (both specific and palliative), they are given.

This treatment includes :

The oral treatment is a solution, which is applied in a concentrated form locally, and in a diluted form as a mouth rinse. It consists of one part that is constant and is selected according to the inherent critical state of the illness. It is made up of four essential oils, two fundamental tinctures, and a spreading and/or dissolving substance. The other part is made up of two essential oils, chosen according to the germ isolated identified, and tested with an aromatogram. It is added to the first part following the outcome of the biological results.

The intra-rectal treatment is prescribed in the form of three daily rectal irrigations for 30 days. It consists one part which is constant and is selected according to the inherent critical state of the illness. It is made up of two essential oils, two fundamental tinctures, an oily support and two trace elements. The second part is made up of two essential oils chosen according to the germ eventually isolated, identified and tested with an aromatogram. It is added to the first part after the outcome of the biological results.

The raw materials will be supplied by a laboratory, which will also select the botanical materials requiered and the magistral preparations will be prepared at the Hospital. Each plant supplied will have its analytical composition attached to it, and in particular, the essential oils, will be given with a gas-phase chromatography identification. Any additional essential oils used will come from the same source in order to offer the same warranties.


DEFINITIONS

Infectious and ulcerative complications of the oro-pharangeal mucosa are nearly constant in patients undergoing chemotherapy at the terminal stages of cancer and AIDS.

CLINICAL FOLLOW-UP (D0, D11, D31)

gingivitis
  • present
  • absent
  • gingivorrhagia
  • present
  • absent
  • hypersiala
  • present
  • absent
  • hyposialia
  • present
  • absent
  • asiala
  • present
  • absent
  • unique aphta
  • present
  • aphtosis
  • present
  • absent
  • gingival neuralgia
  • present
  • absent
  • facial neuralgia
  • present
  • absent
  • gingival neuritis
  • present
  • absent
  • facial neuritis
  • present
  • absent
  • Treatment Tolerance

    a) Local

    b) General

    Treatment observance

    BACTERIOLOGICAL FOLLOW-UP (D0, D31)

    Isolation and identification of the germs with cultures of salivary secretions. If the D0 culture is positive : study of the sensibilities to a predetermined number of essential oils with an aromatogram.

    BIOLOGICAL FOLLOW-UP (D0, D11, D31)

    PRECONDITIONED ORAL MIXTURE

    E.O. according to aromatogram2,5 g
    E.O. according to aromatogram2,5 g
    E.O. clove3,5 g
    E.O. savory3,5 g
    E.O. thyme4,5 g
    E.O. lavender9,5 g
    Tween 802 g
    Juglans regiaTM) aa qsp
    Rubus fructicosusTM) 125 ml
    - One tea-spoon on this mixture dissolved in 30 ml of water applied as a mouth-rinse 4 to 8 times daily.

    PRECONDITIONED INTRA-RECTAL MIXTURE

    E.O according to aromatogram5 g
    E.O according to aromatogram5 g
    E.O. cinnamon5 g
    E.O. savory5 g
    Polygonum bistorteTM)
    Agrimonia eupatoriaTM)aa qsp 125 ml
    Oil of matricaire camomille
    Oil of St John's wort (millepertuis)
    - One tea-spoon of this mixture in 30 ml of the selected decoction, with :
    - 2 ampules of each Granions :
    - Selenium qs
    - Bismusth qs
    all in one rectal irrigation, repeated 3 times daily, for 30 days.

    EXCLUSION CRITERIA
    None

    INCLUSION CRITERIA
    Any cancer and/or AIDS patient, undergoing or following antimitotic, antibiotic or antidepressant treatment, (or any other drug), capable of provoking inflammation, ulcerations and/or infections of the oro-pharangeal cavity.


    ONCOBIOLOGY : index
    ONCOBIOLOGY : EXPERIMENTAL SCHEMES
    ONCOBIOLOGY : OSTEOPOROSIS

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